Feb 01, 2016 WineBottler Combo unknown for Mac is free to download from our software library. The most popular version among WineBottler Combo for Mac users is 1.1. The application's installer is commonly called WineBottlerCombo1.1.44.dmg. The program belongs to Developer Tools. This free Mac app is an intellectual property of kronenberg. On Catalina/Big Sur/etc. You can use homebrew to install either wine-stable or wine-devel (to see all available options run brew search wine). At the moment of writing wine-stable was still too buggy so I went instead with wine-devel. On Catalina/Big Sur/etc. You can use homebrew to install either wine-stable or wine-devel (to see all available options run brew search wine). At the moment of writing wine-stable was still too buggy so I went instead with wine-devel. EDIT: This tutorial video is outdated and will be replaced with a new video which also works on M1 Macs. Use this tutorial video only on Intel Macs and if yo.
give me coffee!
64-bit – Driven by need
With 64-bit only macOS Catalina around the corner and therefore the imminent loss of 32-bit, I had to sort out my toolchain where Wine is still playing a major role.
I therefore rebased my build-environment on macOS High Sierra and XCode 9.4.1. That is the last combination where I can compile both architectures of Wine in one run. As Clang 32-bit is already removed in macOS Mojave. I was able to install the command line tools of XCode 9.4.1 on it, but in the end, I opted for a clean solution. As the already heavy bending of environment variables to build self-contained versions of Wine got to an all-new level with multiple versions of XCode installed :).
But moving up to High Sierra has its price. The new builds will only run on machines with High Sierra or newer. (Let me know if you still need to run WineBottler on older versions of macOS, it might be possible to move one or two incarnations back. Possibly not as far as the now really outdated WineBottler 2.0 or WineBottler 1-8 did. They were still built on OS X 10.6.8 and had a spectacular range of OS versions supported :D).
16-bit, 32-bit and 64-bit
Back to today: The new builds of Wine.app for WineBottler are based on Wine 4.0.1 and come as shared WoW64 builds. They feature the 32-bit and the 64-bit Wine. Even 16-bit programs still work with the current setup. Further, the builds do include Mono (which was already bi-arch) and both architectures of Gecko.
I did some groundlaying work to include 64-bit support into WineBottlers app-building, already: You can easily select the correct operating-system / architecture combination. But things need to get a little bit smarter still to manage the two possible versions of prefixes that are required. I still consider this build preliminary work. Id est I did not test the setup with macOS Catalina, yet. But I plan on moving all my 32-bit Windows-based programs to their 64-bit counterparts anyway, so I'm not concerned with 32-bit too much.
Fixes
Finally, we have landed some UI fixes, too. They remove glitches on macOS Mojave, especially in Darkmode. Further, we have addressed missing icons and problems when selecting the exe to be run.
Look out for the new builds at winebottler.kronenberg.org
Cheers Mike
This is instructions to use the ClampFit from the pClamp suite for ion channel analysis on the Mac. The system this write-up is based on is OSX 10.6 (Snow Leopard), pClamp 10, and uses Winebottler 1.1.44.
By way of introduction, Wine is the general open-source solution for running Windows-based software on UNIX-like systems (for example, Linux and OSX) by providing a compatibility layer underneath the application. Specific implementations for different platforms and applications exist; e.g., CrossOver, Darwine, and Bordeaux. This is advantageous to running pClamp in Bootcamp as you can simultaneously run your OSX software; it is better than running pClamp in Parallels Desktop as it does not require booting up a separate operating system for a single application — not to mention the high combined cost of both the WinOS and Parallels.
As mentioned above, a number of Wine-related apps are available for OSX, some of which are known to be incompatible with pClamp (e.g., CorssOver 8 and 9). Winebottler worked marvelously for me and I’d like to share the procedure. You will need your pClamp installer (it should be named pClamp-10_0_0_79.exe)
(i) Download and launch the .dmg
(ii) Drag both Wine and Winebottler to applications (optional).
(iii) Run Winebottler, and select “Create Custom Prefixes” (ion channels isn’t exactly a household name 😉 )
(iv) Select a file (A), decide if you want Wine to be encapsulated (B), check silent install (C), and Install (D). This will launch first a prompt for the location/name to store the result, then the pClamp installer.
(v) Pick a “destination folder” – this does not matter.
Winebottler For Mac Cnet
(vi) You will see a pair of device driver errors. Ignore them. pClamp suite of software uses a security dongle for verification and the dongle is not supported in Wine. This does not affect ClampFit.
Wine Mac 64 Bit
(vii) In the dialog box, select ClampFit.exe as what should be running in the application.
At this point you should have an app at the location you specified in step (iv). Treat this as any native OSX app – just double click it, and ClampFit should launch:
Congratulations! Now you get to analyse your traces in OSX instead of having to boot up a Windows partition. If you have trouble locating your data files, head all the way up to the desktop first, then go back down into the Users folder.
Winebottler
Comments and feedback are welcome.